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Comment & Response
July 20, 2020

Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 From the Mother to the Infant

Author Affiliations
  • 1Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  • 2Government Medical College, Department of Radiodiagnosis, Hospital, Chandigarh, India
JAMA Pediatr. Published online July 20, 2020. doi:10.1001/jamapediatrics.2020.2132

To the Editor Zeng et al1 made some important observations emphasizing that our knowledge about the natural history of coronavirus disease 2019 (COVID-19) in children (especially neonates) is rapidly changing and is very limited.1 As per recent reports, it takes about 2 weeks for the nasopharyngeal swab results to turn negative, and the fecal viral shedding can last for 2 more weeks.2,3 However, in the index study, the nasopharyngeal as well as anal reverse–transcription polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test results became negative within 5 to 7 days, and that too simultaneously. Does it imply that the fecal shedding in neonates is different and not persistent like children and adults? Can we tell the parents that nappy handling can be safe after a week considering the RT-PCR results?