To the Editor We read with interest the Viewpoint “High-Flow Nasal Cannula Therapy for Pediatric Patients With Bronchiolitis: Time to Put the Horse Back in the Barn”1 and thank the author for her review that broadly agrees with the Paediatric Research in Emergency Departments International Collaborative (PREDICT) network interpretation that the data from the 2 published randomized clinical trials (RCTs)2,3 support the use of high-flow nasal cannula (HFNC) therapy in infants with hypoxia where standard oxygen therapy has failed.4