To the Editor I am writing about the article “Age-Related Differences in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Levels in Patients With Mild to Moderate Coronavirus Disease 2019 (COVID-19)”1 published on July 30, 2020, in JAMA Pediatrics. I have serious concerns about the validity of their suggestion that individuals younger than 5 years may have more coronavirus disease 2019 (COVID-19) RNA. From a review of the Figure in this article,1 for children younger than 5 years, the authors plot 3 outliers among a total number of 46 participants. This is 6.5%. Had they included these outliers, I suspect they would not be able to make their suggestion that children younger than 5 years may have more COVID-19 RNA. Good data analysis does not allow scientists to simply discount data as outliers so that a significant outcome can be suggested. I would have preferred to see a graph with dots for all data points and then indications for the mean and the error bars. Further, the error bars are sufficiently wide and overlapping that I suspect there is not much difference between all the groups. Their suggestion that children younger than 5 years may have more COVID-19 RNA is being cited and amplified as fact over conventional and social media. This can influence important choices about daycare and schools, and I have serious concerns about how the authors analyzed their data.