To the Editor Reliable data for profiles of viral load are needed and important to guide antiviral treatment, infection control, and vaccination. In their interesting article in JAMA Pediatrics, Heald-Sargent and colleagues1 describe that levels of viral nucleic acid in nasopharyngeal swabs are significantly greater in children younger than 5 years compared with older children. The authors report that children younger than 5 years (n = 46), children aged 5 to 17 years (n = 51), and adults aged 18 to 65 years (n = 48) had median cutoff cycle threshold (Ct) values of 11 for older children and adults and 6.5 for children younger than 5 years.
Guterres A. Viral Loads of SARS-CoV-2 in Young Children. JAMA Pediatr. 2021;175(5):528. doi:10.1001/jamapediatrics.2020.5539
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.