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Comment & Response
February 1, 2021

Estimates From Heterogeneous Studies of Opioid-Related Morbidity

Author Affiliations
  • 1Department of Applied Health Science, School of Public Health, Indiana University, Bloomington
  • 2Department of Medicine, Indiana University School of Medicine, Indianapolis
  • 3Department of Psychological and Brain Sciences, Indiana University, Bloomington
JAMA Pediatr. 2021;175(5):532-533. doi:10.1001/jamapediatrics.2020.5625

In Reply We thank Chua et al for their thoughtful comments on our article.1 We concur with much of their Letter and begin with 3 points of agreement.

First, we wholeheartedly agree that decisions to prescribe opioids should be made cautiously, balancing possible benefits with harms, and only in the minimum required quantity. Certainly, risk of diversion to others, although not the focus of our study, is relevant to that balance.

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