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Comment & Response
July 12, 2021

Additional Counseling Support for Mothers With Gestational Hypertensive Disorders Regarding Neurodevelopmental Outcomes in Their Children

Author Affiliations
  • 1Department of Obstetrics and Gynecology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy
JAMA Pediatr. 2021;175(10):1081-1082. doi:10.1001/jamapediatrics.2021.2074

To the Editor We read with interest the article by Brand and colleagues1 investigating risks of autism spectrum disorders (ASDs), attention-deficit/hyperactivity disorder (ADHD), intellectual disability (ID), and variation in overall cognitive performance in offspring of mothers with maternal hypertensive disorders of pregnancy (HDP). In the Swedish register, including data from a birth cohort of individuals born and monitored for a mean of 22 years, Brand et al1 found that HDPs were associated with small increased risks of ASDs and possibly ADHD, whereas associations with ID and cognitive performance were likely confounded by shared familial (ie, environmental or genetic) factors.

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