[Skip to Navigation]
Views 1,935
Citations 0
Research Letter
August 9, 2021

Association of 1 Vaping Session With Cellular Oxidative Stress in Otherwise Healthy Young People With No History of Smoking or Vaping: A Randomized Clinical Crossover Trial

Author Affiliations
  • 1Division of Infectious Disease, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles
  • 2Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles
JAMA Pediatr. 2021;175(11):1174-1176. doi:10.1001/jamapediatrics.2021.2351

Like tobacco cigarette (TCIG) smoking, long-term electronic cigarette (ECIG) vaping in young people is associated with elevated cellular oxidative stress (COS), which is important in the pathogenesis of many diseases, including atherosclerosis.1 As with TCIG smoking,2 even infrequent ECIG use may be associated with adverse biological effects with implications for future health risks. Importantly, the proportion of high school students who have used ECIGs within 1 month of the time of study has skyrocketed, approaching 30% in the US.3,4 The purpose of this study was to evaluate the association of a single session of ECIG vaping on COS in immune cells in young people who do not smoke or vape compared with young people with long-term TCIG or ECIG use.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words