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Comment & Response
January 24, 2022

How to Make Up for Rotavirus Vaccination Missed During the COVID-19 Pandemic?—Reply

Author Affiliations
  • 1HealthPartners Institute, Minneapolis, Minnesota
  • 2Centers for Disease Control and Prevention, Atlanta, Georgia
JAMA Pediatr. 2022;176(4):420. doi:10.1001/jamapediatrics.2021.6019

In Reply The introduction of the rotavirus (RV) vaccine into the routine infant immunization schedule in the US in 2006 led to a marked decline in the incidence of rotavirus disease.1 The vaccine has demonstrated both direct and indirect effects, protecting immunized children from severe illness and hospitalization and reducing community spread of rotavirus. Despite the effectiveness and overall safety of the currently licensed RV vaccines, vaccine coverage in the US plateaued at 71% to 75% from 2013 to 2015.2 In our study evaluating the association of the COVID-19 pandemic and routine childhood vaccination in 8 Vaccine Safety Datalink–integrated health care systems, we observed substantial decreases in weekly vaccine administrations across pediatric age groups from March to September 2020, and the proportion of children up to date with vaccinations decreased most prominently among those turning 7 or 18 months in September 2020.3 We defined vaccine up-to-date status at specified ages per US Advisory Committee on Immunization Practices guidelines but did not evaluate up-to-date status for individual vaccines. RV vaccines were only included in the evaluation of up-to-date status for those reaching 7 months.

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