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May 2, 2022

An Integrated Approach to Blood Culture Stewardship

Author Affiliations
  • 1Baylor College of Medicine, Infectious Diseases Division, Department of Pediatrics, Texas Children’s Hospital, Houston
JAMA Pediatr. Published online May 2, 2022. doi:10.1001/jamapediatrics.2022.1034

Diagnostic stewardship, developed initially to follow the paradigm of antimicrobial stewardship, aims to promote timely and appropriate diagnostic laboratory testing for guiding patient management.1 Excessive testing in patients with a low probability of disease is associated with false-positive results that lead to overdiagnosis, increased health care consumption, and untoward effects such as drug toxicity and the emergence of drug-resistant pathogens. Promoting diagnostic stewardship may lead to improved patient outcomes and cost-effective care. In the intensive care unit setting, diagnostic stewardship applies to key infectious disease diagnoses such as bloodstream infections, urinary tract infections, ventilator-associated pneumonia, and Clostridioides difficile infection.

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