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October 31, 2022

Migraine and Mental Health in Pediatrics

Author Affiliations
  • 1Center for Integrative Brain Research, Division of Pediatric Neurology, Department of Neurology, Seattle Children’s Research Institute, University of Washington School of Medicine, Seattle
JAMA Pediatr. Published online October 31, 2022. doi:10.1001/jamapediatrics.2022.3948

Migraine is one of the most common neurological conditions worldwide, affecting 5% to 10% of younger children and up to 25% of adolescent girls.1,2 Recurrent headaches can be extremely disabling and often prevent children from fully participating in school or extracurricular activities. Despite evidence that pediatric migraine is associated with poor quality of life and is causing a growing global economic burden, many basic questions about migraine management and factors that influence migraine remain unanswered. There is an ongoing need for rigorous studies in pediatric migraine, including an examination of comorbidities, migraine treatment options, and how management of comorbidities, like mood disorders, may affect migraine-related disability and outcomes.1

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