We read with interest the recent article on diagnostic testing for serious bacterial infections in infants with bronchiolitis.1 The authors suggest that previously healthy, well-appearing infants with wheezing and other signs of an upper respiratory tract infection may not need laboratory testing for bacterial infections even in the presence of fever. We describe an infant with pneumococcal bacteremia who presented with the symptoms and signs of bronchiolitis. If the aforementioned recommendations were followed, we would have failed to make an early diagnosis in this infant.