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The Pediatric Forum
July 2005

Incidence of Autism—Reply

Arch Pediatr Adolesc Med. 2005;159(7):690-692. doi:10.1001/archpedi.159.7.691-b

In reply

Dr Fischer's letter highlights the difficulties in interpreting ecologic trends in studies such as this, namely, the potential association between the introduction of a new strain of measles vaccine, the change to a 2-dose MMR vaccination schedule, and the increase in the incidence of autism between 1976 and 1997 reported in our study.1