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May 1951

Het rubella-probleem in het licht van Nederlandse ervaringen.

AMA Am J Dis Child. 1951;81(5):748. doi:10.1001/archpedi.1951.02040030761018

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In this monograph is presented an attempt to evaluate, verify or disprove the theories and reports on the problem of rubella in pregnancy.

The author reviews the Australian, English and American literature and presents the Netherlands approach. On the one hand, German measles occurred significantly oftener during the pregnancy of mothers of deaf-mute children than during those of mothers of normal children born in the same year. On the other hand, they were unable to infer the chance of defective offspring in proved cases, partly because the duration of pregnancy is such a vital factor. Under two months gestation enhances the danger tremendously.

The verification of the diagnosis is reviewed, including blood studies in which the elevation of stab forms and leukopenia, as reported by MacBryde and Charles, are emphasized.

General studies of significance show that women in populated and sparsely populated areas vary in susceptibility to rubella.

The use

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