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November 1951


Author Affiliations

From the Pediatric Department, Jewish Hospital.

AMA Am J Dis Child. 1951;82(5):561-566. doi:10.1001/archpedi.1951.02040040581005

THIS PAPER presents the clinical and pathological findings of generalized arteriosclerosis occurring in a 5-month-old infant. The baby died of myocardial infarction which resulted from multiple coronary occlusions. Since the first case report by Bryant and White,1 in 1891, additional reports have appeared in the domestic and foreign literature.2

REPORT OF A CASE  A 5-month-old white boy was admitted to the Jewish Hospital, Philadelphia, on July 8, 1947, with a chief complaint of cough of three months' duration. The baby had progressed satisfactorily until the age of 8 weeks, when a persistent cough and anorexia developed. Three days before admission the cough became worse, and there was marked irritability. A low-grade fever had been present for one week. In the two months prior to admission there was a 480-gm. weight loss. His vitamin intake was adequate. His mother had rheumatic fever in childhood; however, her pregnancy was uneventful,

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