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November 1951


Author Affiliations

From the service of Harry J. Cohen, M.D., Pediatric Department of the Harlem Hospital of New York City, Morris Gleich, M.D., Director.

AMA Am J Dis Child. 1951;82(5):574-578. doi:10.1001/archpedi.1951.02040040594007

NEUROFIBROMATOSIS of von Recklinghausen is considered to be infrequent in children. Leader and Grand1 reviewed a series of reported cases of children and noted that the disease is as frequent in the male as in the female and that it is usually first noticed, if not at birth, between the ages of 2 and 6 yr. In the early stages, in childhood, the cutaneous pigmentation may be the only manifestation of the disorder, and frequently, because there are no associated signs, the diagnosis is not made. Many years ago Weber2 called attention to cases in which pigmentation of the skin became evident long before the appearance of neurofibromas of the nerve trunks. In view of the rarity of nodular formation (neurofibromas) at birth, the following case is being presented.

REPORT OF A CASE  G. F. C. (50-14819), Negro girl weighing 2,500 gm., was born on Aug. 6, 1950.

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