AFTER the development of a practical clinical method for measuring chloride balance,1 this technic was applied to pediatric patients in order to evaluate it as a diagnostic aid and therapeutic guide in the parenteral administration of fluid and electrolyte. The results of this preliminary study will be published later. This report is of a case of water intoxication in which the cumulative-chloride-balance study was believed to contribute to the diagnosis and therapy.
REPORT OF CASE
A 7-month-old girl infant who weighed 8,800 gm. and was 72 cm. long was hospitalized because of exstrophy of the urinary bladder. Physical examination revealed a well-developed and well-nourished infant with no additional abnormalities. Preoperative blood chemistry determinations, including a value for blood urea of 38 mg. per 100 cc., were within normal limits. A cumulative-chloride-balance study was started at 11 a. m. on July 18, 1950, when the infant had just been
BASKIN JL, KEITH HM, SCRIBNER BH. WATER INTOXICATION: Report of Case in Which Cumulative-Chloride-Balance Data Aided Diagnosis and Therapy. AMA Am J Dis Child. 1952;84(3):351–354. doi:10.1001/archpedi.1952.02050030077009
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