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Article
January 1953

PROLONGED OBSTRUCTIVE JAUNDICE IN INFANCY: III. Liver Function Tests

Author Affiliations

BOSTON
From the Medical Service of the Children's Medical Center, the Department of Pediatrics of the Beth Israel Hospital, and the Department of Pediatrics of the Harvard Medical School. Aided by a grant from Mead Johnson & Company.

AMA Am J Dis Child. 1953;85(1):13-19. doi:10.1001/archpedi.1953.02050070020002
Abstract

IN A PREVIOUS report,1 we have reviewed the cases of 156 infants admitted to the Children's Medical Center because of prolonged obstructive jaundice. This series consisted of 94 cases of biliary atresia, 23 cases of inspissated bile due to erythroblastosis, 30 cases of inspissated bile of unknown cause, 4 cases of infectious hepatitis, and 5 cases of obstructive jaundice due to miscellaneous causes. The present study is an analysis of the liver function tests performed on these infants and an attempt to demonstrate the usefulness and limitations of these tests in the differential diagnosis of obstructive jaundice in infancy.

METHODS AND MATERIALS  The criteria for the selection of cases have been presented previously. The series as a whole included all of the cases of infants who were thought to have prolonged jaundice due to some type of obstruction; most of the infants were admitted to the hospital with a

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