FROM A study of 600 adults with migraine1 it was noted that the onset of headache frequently occurred in childhood and also that psychological factors played a prominent role in the production of the migraine attack. As a result of these observations a group of 50 children with migraine who were seen at the Headache Clinic of the Montefiore Hospital for Chronic Disease, were studied in an effort to evaluate the syndrome. A preliminary study has been published.2 By "migraine" we mean that form of recurrent headache which is characteristically unilateral, occurs in bouts usually associated with gastrointestinal and/or ocular symptoms against a background of relative well-being, and is often preceded by visual or psychological disturbances and followed by sleep. There is usually a history of similar headaches in the parents or other members of the family.
The underlying causes of migraine are unknown. However, the mechanism of
KRUPP GR, FRIEDMAN AP. MIGRAINE IN CHILDREN: A Report of Fifty Children. AMA Am J Dis Child. 1953;85(2):146–150. doi:10.1001/archpedi.1953.02050070155003
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