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March 1953

Phenol and Its Derivatives: The Relation Between Their Chemical Constitution and Their Effect on the Organism.

AMA Am J Dis Child. 1953;85(3):389. doi:10.1001/archpedi.1953.02050070401011

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This volume seemingly gives the complete literature on the chemistry, pharmacology, toxicology, and treatment of poisoning, stressing the therapeutic action of the many compounds derived from phenol.

As stated in the introduction, often systematic changes of the molecule have revealed certain trends with regard to physiologic or toxicologic effects. In the present work, these changes are discussed to give a better understanding of the mechanism of the action of such compounds.

There are 55 pages of references, a total of approximately 1,300. The phenolic and aldehyde acids, with the exception of salicylic acid, have such slight physiologic action that a discussion of them is therefore omitted. Salicylic acid has retained so little of the phenolic action and its literature is so extensive that it is not included in this volume. The volume is compiled by a well-known able pharmacologist and is written in a clear simple style. It should prove

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