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May 1953

PERIARTERITIS NODOSA: Report of a Case of Apparent Recovery in a Nine-Year-Old Boy During Cortisone Therapy

Author Affiliations

From the Children's Clinic; the Southern Baptist Hospital, and the Department of Pathology and the Department of Pediatrics, the Tulane University of Louisana School of Medicine.; Instructor in Pathology and in Pediatrics, Tulane University of Louisiana School of Medicine, member of the Pediatrics Staff, Southern Baptist Hospital, and Visiting Pediatrician, Charity Hospital of Louisiana and Sara Mayo Hospital (Dr. Dent); Visiting Pediatrician, Touro Infirmary and Southern Baptist Hospital and Consultant in Pediatrics, Flint Goodridge Hospital (Dr. Strange); Visiting Pediatrician, Southern Baptist Hospital; formerly Chief of the Independent Pediatric Service, Charity Hospital of Louisiana, Instructor in Pediatrics, University of Minnesota, Assistant Professor of Pediatrics, Louisiana State University School of Medicine, and Associate Professor of Pediatrics, University of Texas School of Medicine, Galveston (Dr. Sako); member of the Pediatrics Staff, Southern Baptist Hospital and Hotel Dieu and Assistant Visiting Pediatrician, Charity Hospital of Louisiana (Dr. York).

AMA Am J Dis Child. 1953;85(5):556-565. doi:10.1001/archpedi.1953.02050070571005

PERIARTERITIS nodosa has no typical course. It resembles various other diseases and is seldom proved during life. It is therefore an alternative to be considered in diagnosing many of the illnesses of childhood.1

Analyzing 42 cases of periarteritis nodosa in children (as found in the literature) Keith and Baggenstoss2 listed the following symptoms in order of frequency: fever, usually intermittent; leucocytosis; abdominal pains; rheumatic pains; renal disease; general weakness; convulsions; tachycardia; anemia; purpuric rash; other rashes, chiefly urticaria; hypertension; tonsillitis or sore throat; headaches; intestinal hemorrhage; peripheral gangrene; signs of meningeal irritation; palpable nodules.

The small number of cases recorded (less than 500 among adults, less than 60 among children) may be attributed partly to the rarity of the disease and partly to the difficulties of recognition. Even when diagnosis is established, death usually follows. No specific therapy is known.

In this disease of the

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