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September 1953

STUDIES IN RESPIRATORY INSUFFICIENCY: I. Carbon Dioxide and Oxygen Studies in Early Respiratory Paralysis in Poliomyelitis

Author Affiliations

From the Poliomyelitis Respirator Center, Department of Pediatrics, University of Michigan Medical School.

AMA Am J Dis Child. 1953;86(3):265-272. doi:10.1001/archpedi.1953.02050080275001

IN THE last few years, because of availability of artificial aids to respiration, a great deal of attention has been given to the early detection of insufficiency of respiration, particularly in the narrow field of respiratory involvement in poliomyelitis.1

There exist considerable differences of opinion as to the proper time at which a patient with early respiratory muscle paralysis in poliomyelitis should be given artificial aid. It has been argued that the early use of a respirator increases the risk of addiction to the respirator and the chance of the patient's developing an excessive pulmonary ventilation, on which he becomes dependent because of the early use and its excessive use. On the other hand, many believe that the early use of the respirator, if it succeeds in giving rest, is of advantage.2

It has been our hope to develop laboratory techniques which would detect early respiratory insufficiency before

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