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December 1953

Streptomycin Treatment of Acute Tuberculosis in Children: A Report on the Meeting of Experts Organized by the UNICEF and WHO, Paris, 9-12 February 1950.

AMA Am J Dis Child. 1953;86(6):844. doi:10.1001/archpedi.1953.02050080859017

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The book contains 16 papers presented by experts from various countries on acute tuberculosis in children. Most of the papers, however, deal with tuberculous meningitis. There is only one paper on miliary tuberculosis and another on alterations of the pathologic anatomy of tuberculous lesions due to the action of streptomycin.

Although the keynote of the book is treatment, the whole field of tuberculous meningitis is covered. There are chapters on diagnosis, cerebrospinal fluid changes, prognosis, ophthalmologic examinations, and sequelae. There is also a chapter on electroencepholography in tuberculous meningitis.

The greater portion of the discussion on treatment is on streptomycin, such as dosage, the route of administration, and the period of treatment.

At the end of the book are general recommendations which reflect the opinion of all the experts in the field. The streptomycin dosage recommended is 20 to 50 mg. per kilogram of body weight in 24 hours, with

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