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April 1954

INCIDENCE OF "SUBCLINICAL" TRICHINOSIS IN CHILDREN: Observations Based on Reaction to Intradermal Test with Trichinella Antigen

Author Affiliations

From the Department of Pediatrics, Howard University College of Medicine, and the Pediatric Service of Freedman's Hospital.

AMA Am J Dis Child. 1954;87(4):464-467. doi:10.1001/archpedi.1954.02050090452005

TRICHINOSIS has been studied for more than 100 years and has caused many epidemics throughout this country. Despite this fact, there is a paucity of data regarding the incidence of this infection in American children.

Ströbel,1 in 1911, introduced the first immunologic test for the diagnosis of trichinosis. This method was not widely used until 1928, when Bachmann * improved the antigen and described a precipitin test as well as an intradermal reaction in rabbits and guinea pigs infected with Trichinella. Between 1932 and 1941, other workers † studied the Bachman intradermal test and made various modifications. They concluded that patients with trichinosis gave an immediate positive skin reaction 11 to 43 days after infection in 74 to 98% of cases.

Sawitz,8 in 1937, skin tested 200 patients using Trichinella antigen and found 5% had positive reactions. None of these persons gave a clinical history of trichinosis. Rose and Culbertson,

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