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August 1954

A Study of Normal and Pathologic Variants: II. Patterns of A and B Isoantibodies in the Cord Blood of Normal Infants

Author Affiliations

From the Children's Hospital, The Child Research Center, and the Department of Pediatrics, Wayne University College of Medicine, Detroit.

AMA Am J Dis Child. 1954;88(2):179-192. doi:10.1001/archpedi.1954.02050100181004

IN THE PRECEDING paper,1 the anti-A and B isoantibody patterns of unselected women in homospecific and heterospecific pregnancies were described. The present paper deals with the infants born to those mothers and is concerned with the isoantibodies of the cord bloods and their relationship to the maternal isoantibodies. The methods used were the same as those described in the first paper.

OBSERVATIONS  Homospecific Pregnancies.–Cord bloods for isoantibody studies were available from 69 of the 92 Group O infants of O mothers. In 23 cases the cord serum could not be obtained either because the child had been delivered at home or in another hospital or because of accidental losses in collecting the samples. The results of the anti-A and anti-B titrations of the 69 cord sera are given in Table 1, together with the corresponding maternal titers drawn within 24 hours after delivery. It will be seen that

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