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February 1955

ALLERGENICITY OF MODIFIED AND PROCESSED FOODSTUFFS: V. Soybean; Influence of Heat on Its Allergenicity; Use of Soybean Preparations as Milk Substitutes

Author Affiliations

New York; Memphis; Manchester, Conn.; New York
Formerly Research Fellows in Pediatric Allergy (Drs. Crawford, Malone, and Retsina).; From the Departments of Pediatrics and Immunology, New York Medical College and Flower and Fifth Avenue Hospitals, and the Pediatric Division of Sea View Hospital, New York.

AMA Am J Dis Child. 1955;89(2):187-193. doi:10.1001/archpedi.1955.02050110229008

SINCE the admonition of Duke1 20 years ago that soybean might be a prominent cause of allergy, there has been an extraordinary dearth of reports of instances of allergy attributable to its use. This may be explained by the observation of Hill2 that soybean is a weak antigen.

Hill's idea is corroborated by a report received from a manufacturer of soybean and corn products.* The information came in response to a question relative to allergy encountered among employees. In seven years there have been only 2 cases of soybean allergy of the asthmatic type among 1500 employees who were exposed to soybean fumes and dust in the air. These two persons were skin tested and found sensitive to soybean flour. Attacks of asthma were precipitated by contact with soybean dust. It was further asserted that two or three persons per year attributed skin rashes to the handling of

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