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March 1955

The Use of Warm Blood for Exchange Transfusions

Author Affiliations

Schenectady, N.
From the General Electric Research Laboratory (Dr. Wilson).

AMA Am J Dis Child. 1955;89(3):289-291. doi:10.1001/archpedi.1955.02050110355004

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INTRODUCTION  There are many factors which affect the condition of an infant during an exchange transfusion. To date little thought has been given to the possibility of the adverse effect which may be caused by the introduction of a large volume of cold blood into an infant's circulatory system. Regardless of the temperature of the blood in the reservoir, it approaches room temperature as it is given to the baby. This is due to the relatively small calibre of the tubing, which exposes a large surface of a small volume of blood to the ambient temperature. We have observed that the temperature of the blood at the point of introduction into the umbilical vein varies from 70 to 80 F. It is necessary for the infant to supply enough heat to raise the temperature of 500 cc. of blood 18 to 28 degrees.Different methods of preventing the loss of

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