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June 1955

Hemodialysis of the Uremic Child

Author Affiliations

Established Investigator of the American Heart Association (Dr. Mateer).; From the Children's Hospital, Pittsburgh, and the Department of Research Medicine, University of Pittsburgh School of Medicine.

AMA Am J Dis Child. 1955;89(6):645-655. doi:10.1001/archpedi.1955.02050110785001

Vividialysis has proved itself useful in adults with renal disorders in which the fluid disturbances of uremia threaten life before reparative processes can restore kidney function. Two methods of dialysis have been employed: (1) lavage of a membrane within the body, either the peritoneum or an isolated loop of bowel, by dialyzing fluid,* and (2) extracorporeal hemodialysis in an artificial kidney using cellophane to separate the patient's blood from the lavage fluid.† Although the number of such dialyses performed in adult subjects can now be counted in hundreds,‡ the use of either method in therapy of children with far-advanced renal failure has been relatively infrequent. Peritoneal lavage in three uremic children was described by Swan, in 1949.14 However, due to various difficulties reported, such as occlusion of the siphon apparatus, loss of body protein, inability to regulate transfers of water and of electrolytes, and the danger of infection, we

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