Hashimoto's struma, or struma lymphomatosa, is considered to be a disease of the fifth and sixth decades, but it nevertheless can occur over a wide range of age. In their excellent review of the material from the Massachusetts General Hospital, Statland, Wasserman, and Vickery1 reported 51 cases between the ages of 10 and 74 years. All were females. Two of their cases occurred at the age of 10 years, one at the age of 14 years; a fourth patient, who had a goiter since the age of 12, was diagnosed as having Hashimoto's struma at the age of 21. Gribetz, Talbot, and Crawford added three additional adolescent cases in 1954 and collected 11 others from the literature.2 Standard textbooks rarely refer to the possibility of this disease in childhood. It is probable, however, that the incidence in the pediatric age group is higher than generally conceded.
DAVIS HC, HANSKE EA. Hashimoto's Disease in Childhood. AMA Am J Dis Child. 1955;90(2):173–175. doi:10.1001/archpedi.1955.04030010175007
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