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April 1956

Muscular Dystrophy: II. Radiologic Findings in Relation to Severity of Disease

Author Affiliations

From the Children's Hospital and the Departments of Pediatrics, Radiology, and Research Medicine, University of Pittsburgh School of Medicine.

AMA Am J Dis Child. 1956;91(4):339-345. doi:10.1001/archpedi.1956.02060020341003

Changes demonstrable by x-rays occur in the long bones, spine, and soft tissues of patients with muscular dystrophy.* Most authors have regarded these findings as part of the disease; they have not correlated them with the severity of the disease. Lewitan and Nathanson15 pointed out that, "the bone changes are purely secondary to the muscle involvement."

The hospitalization of a group of children with muscular dystrophy has provided the opportunity for a study correlating the radiographic changes with the severity of the disease.

MATERIAL AND METHODS  Roentgenograms of the vertebral column, skull, long bones, wrists, and thorax were made of 31 children whose history, physical findings, laboratory studies, and muscle biopsy were compatible with the diagnosis of juvenile form of muscular dystrophy. Films of the spine were examined for signs of scoliosis, lordosis, kyphosis, and "caninization" (i. e., apparent increase in the altitude of the vertebral bodies) and films