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June 1956

Glomerulonephritis in Miami, Florida: Studies on Types 12, 4, and Red Lake Group A Beta-Hemolytic Streptococci Isolated over a Three-Year Period (1953-1955)

Author Affiliations

Miami, Fla.
From the Department of Medical Research, National Children's Cardiac Hospital and the University of Miami School of Medicine.

AMA Am J Dis Child. 1956;91(6):555-560. doi:10.1001/archpedi.1956.02060020557005

Evidence has been accumulating that acute hemorrhagic glomerulonephritis may occur as a nonsuppurative complication following infection with some strains of certain types of Group A β-hemolytic streptococci. Types 12 and 4, especially, have been implicated in this way,1 although it is recognized that not all strains of these types are nephritogenic.2 Other types3 also have been found to produce nephritis. A new type was recently isolated in an epidemic at Red Lake, Minn.*

Many strains of Types 12, 4, and Red Lake were isolated from the throats of school children during a long-term study of the streptococcal epidermiologic pattern in Miami, Fla.† We therefore tried to evaluate these findings in relation to the incidence of nephritis in this area.

MATERIAL AND METHODS  From February through May, 1953, from October, 1953, through May, 1954, and from October, 1954, through May, 1955, pairs of throat swabs were taken monthly

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