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June 1956

Renal Tubular Disease with Nephrocalcinosis: Report of Two Unusual Cases

Author Affiliations

Montreal, Canada
From the Montreal Children's Hospital.

AMA Am J Dis Child. 1956;91(6):601-605. doi:10.1001/archpedi.1956.02060020603014

Disorders of renal tubular function have received increasing attention in recent years, both from the clinical standpoint and because of their importance in clarifying renal tubular physiology. The present report concerns two patients, both of whom showed evidence of renal tubular disease together with renal medullary calcification (nephrocalcinosis). The clinical manifestations, however, were strikingly different and included certain unusual and confusing features which may be of interest.

REPORT OF CASES  Case 1.—A boy aged 8 weeks was admitted to the hospital because of vomiting and failure to thrive, with hematemesis on the day of admission.The patient was the product of the mother's fourth pregnancy, which was complicated by mild toxemia. There was no relevant family history. Delivery, at another hospital, was spontaneous. The birth weight was 2880 gm. The baby was discharged on the seventh hospital day, apparently in good condition.Progress after discharge, however, was consistently unsatisfactory. Frequent

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