This article is a report on an outbreak of pharyngoconjunctival fever due to APC Type III virus which occurred in a children's camp during the summer of 1955. The adenopharyngeal conjunctival or APC group of viruses was isolated in 1952 by Huebner, Rowe, Bell, and others.* They studied surgically removed tonsils and adnoids by tissue culture technique. Through repeated subculturing of these tissues, they were able to unmask a new group of viruses. Because of the characteristic tissue culture degenerating effects produced by these micro-organisms, they were originally named "adenoid-degenerating agents". This was later renamed "adenoidal-pharyngeal-conjunctival viruses" or "APC viruses." As a result of the work first done in the U. S., investigation has been undertaken along similar lines in other countries. Zaiman and co-workers,5 in England, have also been able to isolate this new group of viruses from surgically removed tonsils and adenoids and have noted the presence
SOBEL G, ARONSON B, ARONSON S, WALKER D. Pharyngoconjunctival Fever: Report of an Epidemic Outbreak. AMA Am J Dis Child. 1956;92(6):596–612. doi:https://doi.org/10.1001/archpedi.1956.02060030590009
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: