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February 1957

Die Genuine Vitamin-D Resistente Rachitis.

AMA Am J Dis Child. 1957;93(2):214. doi:10.1001/archpedi.1957.02060040216016

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To this reviewer's knowledge this is the first attempt to present in definitive monographic form the subject of vitamin D-resistant rickets. The clinical and roentgenologic aspects are presented in detail as are the problems of medical and orthopedic management. The literature on the subject is well and completely covered. The authors rather extended experience with 11 cases of D-resistant rickets is given in some detail. Original comparative data on the renal clearance of phosphorous in normal persons and in patients with D-deficient and D-resistant rickets before and after the administration of vitamin D are presented. Data are presented indicating abnormal quantitative distributions of ATP and phosphocreatine in the erythrocytes of patients with the disease. The nature of the enzymatic deficit is speculated about. This monograph will be of value to those who must care for children with the disease and of particular interest to those interested in the basic problems

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