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May 1957

Mild Neonatal Toxoplasmosis: Case Report with a Four-Year Serologic and Dermal Sensitivity Study

Author Affiliations

Great Neck, N. Y.
Department of Pediatrics, Cornell University Medical College and New York Hospital.

AMA Am J Dis Child. 1957;93(5):563-567. doi:10.1001/archpedi.1957.02060040565012

Congenital toxoplasmosis is a generalized infectious disease in humans and animals caused by the protozoan, Toxoplasma gondii, which is transmitted transplacentally from the mother to the fetus. Signs of the disease may become apparent in utero or within a few days, weeks, or months after birth. That human congenital Toxoplasma infections may be mild or asymptomatic as well as severe and fatal is not well known. Most of the congenital toxoplasmosis cases reported in the literature have been severe or fatal infections either with clinical signs of central nervous system damage, such as chorioretinitis, psychomotor retardation or disturbances, cerebral calcifications, and hydro- or microcephaly, or visceral manifestations of jaundice and hepatosplenomegaly or any combination of the above.1 A definite diagnosis can be established by adequate serologic tests2,3 or by demonstrating the parasite in body fluids or tissues. The following case of congenital toxoplasmosis is considered of value because

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