Congenital toxoplasmosis is a generalized infectious disease in humans and animals caused by the protozoan, Toxoplasma gondii, which is transmitted transplacentally from the mother to the fetus. Signs of the disease may become apparent in utero or within a few days, weeks, or months after birth. That human congenital Toxoplasma infections may be mild or asymptomatic as well as severe and fatal is not well known. Most of the congenital toxoplasmosis cases reported in the literature have been severe or fatal infections either with clinical signs of central nervous system damage, such as chorioretinitis, psychomotor retardation or disturbances, cerebral calcifications, and hydro- or microcephaly, or visceral manifestations of jaundice and hepatosplenomegaly or any combination of the above.1 A definite diagnosis can be established by adequate serologic tests2,3 or by demonstrating the parasite in body fluids or tissues. The following case of congenital toxoplasmosis is considered of value because
STILLERMAN M. Mild Neonatal ToxoplasmosisCase Report with a Four-Year Serologic and Dermal Sensitivity Study. AMA Am J Dis Child. 1957;93(5):563–567. doi:10.1001/archpedi.1957.02060040565012
Customize your JAMA Network experience by selecting one or more topics from the list below.