[Skip to Content]
[Skip to Content Landing]
July 1958

Primary Interstitial Myocarditis: Report of an Epidemic Outbreak

Author Affiliations

Haifa, Israel
From the Department of Pediatrics B (Head, Dr. W. Falk) and Department of Pediatrics A (Head, Dr. J. Bar-Hay), Rambam Government Hospital.

AMA Am J Dis Child. 1958;96(1):43-50. doi:10.1001/archpedi.1958.02060060045008

The acute isolated interstitial (Fiedler's) myocarditis is a well-known clinical and pathological entity. It was first described by Fiedler in 1899 in an adult; later, by Zuppinger and by Forster in children,1 and since then a great number of case reports have appeared in the literature. This type of interstitial myocarditis should be diagnosed only in the absence of any other pathological conditions that might be correlated with the myocardial involvement.2,3 The cause of this disease has never been clearly understood. Many theories have been proposed, and an infectious origin has also been considered possible.4,5 However, epidemic outbreaks of interstitial myocarditis have only recently been described.

The first report of an epidemic outbreak came from Munich, Germany, where 140 cases of interstitial myocarditis in infants were observed during the years 1937-1944.6,7 The epidemiological pattern was believed by the author to suggest an epidemic due to a