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May 1959


AMA Am J Dis Child. 1959;97(5_PART_I):653. doi:10.1001/archpedi.1959.02070010655017

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This competent and authoritative text on the pathology of central nervous system diseases represents the last major professional contribution of Dr. J. G. Greenfield, whose untimely death occurred shortly after the first edition became available.

In the initial chapters, the normally encountered histologic structures are carefully described. The spectrum of fundamental changes exhibited by ganglion cells under the influence of numerous agencies is also elaborated. In conjunction with this chapter, there is a lucid description of the various forms of particulate intracellular structures (inclusion bodies) characteristic of the central nervous system. Neuroglial embryology, morphology, and response to disease processes are meticulously assessed.

In the succeeding 12 chapters, various major categories of nervous system diseases are reviewed. (The problem of neural neoplasia is left in abeyance for a subsequent volume.) The first of these segments explores vascular abnormalities (insufficiency, hemorrhage, specific vascular disturbances, and aneurysms). The chapter concerning infectious processes within

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