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June 1960

Encephalopathy in Salmonella Infections

AMA Am J Dis Child. 1960;99(6):770-777. doi:10.1001/archpedi.1960.02070030772012

Different neurological complications of typhoid are known to occur. A bacterial invasion of the meninges, a true bacterial meningitis, is rare and occurs mainly below 2 years of age.14 Peripheral neuritis, radiculitis, and radiculomyelitis, occasionally from the ascending type,7,8 and finally cases of brain involvement have been described.1,4,11,12 Some authors speak of encephalitis, others of encephalopathy; the latter is probably more correct. However, all these complications are rare. It is the purpose of this paper to present five cases of encephalopathy in Salmonella infections observed at the American University Hospital in Beirut. During this period of time about 150 cases of uncomplicated salmonellosis were admitted to this institution. However, these two figures do not permit a conclusion as to incidence of Salmonella encephalopathy, since many milder and even some of the severe cases are not hospitalized.

Case 1.—Fatal Encephalopathy Due to Paratyphoid B with Coma, Electrolyte