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August 1960

Cat-Scratch Disease in Minnesota: I. Evidence for Its Epidemic Occurrence

Author Affiliations

From the Pediatric Research Laboratories of the Variety Club Heart Hospital, University of Minnesota.; Research Fellow, American Heart Association (Dr. Warwick). American Legion Memorial Heart Research Professor of Pediatrics (Dr. Good).

Am J Dis Child. 1960;100(2):228-235. doi:10.1001/archpedi.1960.04020040230011

Cat-scratch fever, a nonspecific regional lymphadenitis unknown in the medical literature prior to 1950, is now being recognized in all parts of the world. This report of 12 and 6 cases, occurring in the winters of 1955 and 1956 in the Minneapolis-St. Paul area, should alert physicians in this area to this disease as a cause of nonbacterial lymphadenitis, and it should alert physicians everywhere to the possible existence of such epidemic outbreaks.

Previous Incidence  The previous incidence of cat-scratch fever in the Minneapolis-St. Paul area is unknown. Prior to this study, there had been only one reported case from this region.1 There is reason to assume that catscratch fever is not a new disease here, in that there is a relatively constant incidence of nonspecific granulomatous disease of lymph nodes observed from year to year by Twin City pathologists in the biopsy specimens they examine. Many of these

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