The use of soybean preparations in human nutrition has received much attention in the past 50 years. In 1909, Ruhräh1 suggested the use of a soybean gruel or milk as a valuable addition to the diet of the sick infant. More recently, however, this legume has had its principal use as a food for allergic infants.2-9 The successful growth and reproduction of animals fed a soybean base formula was reported separately by Daniels and Nichols10 and by Osborne and Mendel11 in 1917. Howard and co-workers12 have reported the support of reproduction and lactation in several generations of animals fed a soybean infant food (Mull-Soy, Powdered).
In 1929, Tso13 fed newborn infants a soybean mixture until they were between 6 and 9 months of age. One was started at birth and five at a few weeks of age. The weight curves on these infants followed
JACOB L. KAY, C. WILLIAM DAESCHNER, MURDINA M. DESMOND. Evaluation of Infants Fed Soybean and Evaporated Milk Formulae from Birth to Three MonthsA Comparison of Weight, Length, Hemoglobin, Hematocrit, and Plasma Biochemical Values. Am J Dis Child. 1960;100(2):264–276. doi:10.1001/archpedi.1960.04020040266017