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February 1961

Immunofluorescence as a Diagnostic Tool: Guest Editorial

Author Affiliations

The Child Research Center of Michigan, Detroit 2

Am J Dis Child. 1961;101(2):137-139. doi:10.1001/archpedi.1961.04020030001001

There is good reason to believe that with the introduction of fluorescent antibody (FA) techniques into the diagnostic laboratory, we are on the threshold of a new era in the diagnosis and control of infectious diseases. This is of primary concern to the pediatrician and now is the time to assess this new tool, to exploit its possibilities, and to avoid misconceptions as to its use.

Already a significant number of applications of the techniques of immunofluorescence to diagnostic problems have been made. Enteropathogenic Escherichia coli serotypes can be identified directly in fecal smears, Group A streptococci in pharyngeal smears, Hemophilus influenzae in smears of spinal fluid, Bordetella pertussis in nasopharyngeal smears, and gonococci in smears of urethral exudates. Reports of these applications have appeared in this journal, including the contribution by Kendrick, Eldering, and Eveland appearing in this issue. Other pathogens have been studied similarly in animals

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