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March 1961

Achromobacter Septicemia—Fatalities in Prematures: I. Clinical and Epidemiological Study

Author Affiliations

From the Kansas City Field Station, Communicable Disease Center, Bureau of State Services, Public Health Service, U.S. Department of Health, Education and Welfare (Dr. Foley, Mr. Gravelle, Dr. Chin); Dr. Foley at present is a Fellow,; Department of Medicine, University of Minnesota; Dr. Englehard is Associate Professor, Department of Bacteriology, University of Nebraska.

Am J Dis Child. 1961;101(3):279-288. doi:10.1001/archpedi.1961.04020040007003

Introduction  In a 3-month period during 1958, 6 infant deaths were reported from a 100-bed hospital in Lincoln, Neb. The illness was characterized by apnea, cyanosis, and an erythematous rash which began on the cheek and extended to the chest. A gram-negative bacterium was isolated in antemortem blood cultures from 3 of the infants, and in a postmortem blood culture of another infant.This bacterium could not be identified or readily classified using standard bacteriological methods. The unusual clinical illness associated with this unidentified bacterium prompted further investigation. The data presented in this paper describe the clinical and epidemiologic aspects of the study. The characteristics of the bacterium will be reported in detail in a separate publication.1

Methods of the Study  The clinical data were obtained by reviewing hospital charts and by examination of the last case. Hospital records were reviewed to obtain the annual number of births, deaths,