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June 1961

Unclassified Mycobacteria in Children: Correlation of Skin Tests and Gastric Cultures

Author Affiliations

Associate Professor of Pediatrics, Medical College of Virginia.; From the Department of Pediatrics and the Child Chest Clinic, Medical College of Virginia.

Am J Dis Child. 1961;101(6):749-755. doi:10.1001/archpedi.1961.04020070063009

In two earlier studies, it was noted that the tuberculosis infection rate among patients attending the well baby clinic at the Medical College of Virginia was extremely high.1,2 Although some question was raised as to the possibility that some of these positive tuberculin reactions might be the result of some cause other than infection with Mycobacterium tuberculosis,3 no evidence was available to support such a theory. While the following material will not necessarily produce this support, it does suggest the widespread incidence of anonymous or unclassified Mycobacteria among children in the Richmond area.

The present study was actually instituted in an effort to determine the effect of isoniazid on primary tuberculosis as determined by eradication of tubercle bacilli from gastric culture. Results of this investigation will be reported more fully in another publication.

Criteria for the Study  Admitted to the study were 105 children with diagnosis of asymptomatic