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August 1961

On Interval Exchange Transfusions: The Effect of Tubing Dead Space

Author Affiliations

Chester Trossman, M.D., 3507 Alma St., Palo Alto, Calif.; Frederick E. Alzofon is affiliated to Lockheed Aircraft Corporation, Sunnyvale, Calif.

Am J Dis Child. 1961;102(2):194-198. doi:10.1001/archpedi.1961.02080010196007

Introduction  This paper is concerned with the effect of tubing dead space on interval exchange transfusions. By "tubing dead space," we refer to the volume in the tubing connecting the exchange transfusion syringe to the patient's blood circulation. The latter aspect was not discussed in a previous paper by 2 of us1 and it is desirable to emphasize the necessity of improving the efficiency of a given transfusion by decreasing dead space to a minimum. Moreover, since publication of the reference cited,1 a question has been raised as to the effect of tubing dead space2; this paper seeks to provide a definitive evaluation of the effect of tubing dead space.A simple example, based on a frequently encountered situation among those requiring exchange transfusions, serves to illustrate the importance of minimizing dead space. Figures 1 and 2 graphically demonstrate the increase in the number of unit exchanges

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