The following case of the Guillain-Barré syndrome is believed to be of one of the youngest patients reported in the literature. A review of both the English and the French literature1 in 1941 revealed that a 2-year-old was the youngest documented case then. In 1957, Chambers and MacDermot2 reported a case of acute polyneuritis causing "amyotonia congenita" starting at 3 months of age, but whether or not this case fits the criteria of the Guillain-Barré syndrome is questionable, and will be discussed subsequently. In a study relating to the clinical value of motor nerve conduction velocity determination,3 a case of a 6-month-old infant is presented, with infectious neuronitis but no spinal fluid finding included in the protocol, and so again the diagnosis of Guillain-Barré syndrome may be open to question. Aside from the above-mentioned 2 cases, the youngest previously reported case of the Guillain-Barré sydrome was in
EDEN AN. Guillain-Barré Syndrome in a Six-Month-Old Infant. Am J Dis Child. 1961;102(2):224–227. doi:10.1001/archpedi.1961.02080010226012
Customize your JAMA Network experience by selecting one or more topics from the list below.