Association of hemangioendothelioma with thrombocytopenic purpura has been described repeatedly.1,2 The tumor is usually obvious at birth. Radiation therapy has been thought to be of value; surgical removal of the tumor has been performed3; splenectomy is apparently not beneficial. As the tumor shrinks, purpura ceases, and platelet counts return to normal. There are a few reports of spontaneous involution of cavernous hemangioma.4 The interest in the following case revolves about the spontaneous regression of a huge hemangioma with thrombocytopenic purpura in the first 6 months of life.
The patient, a boy, was admitted to Children's Hospital, at the age of 3 days, because of jaundice, hematemesis, and a large tumor on the left leg. He was born of a full-term pregnancy; normal delivery. His birth weight was 3175 gm. (7 lb.); there was no neonatal distress. Jaundice was noticed at 12 hours. The patient vomited
WALLERSTEIN. RO. Spontaneous Involution of Giant Hemangioma: Simultaneous Regression of Tumor and Thrombocytopenia in Newborn. Am J Dis Child. 1961;102(2):233–235. doi:10.1001/archpedi.1961.02080010235014
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