During the decade (1950-1960), at the Los Angeles Children's Hospital, survival after the primary repair of esophageal atresia of the usual type (Gross, C; Ladd, III), in infants without other anomalies and weighing more than 3 kg. has approached 95%. A similar trend is reported from other pediatric centers throughout the world.3,10-14
At the same time (and in the same institutions), however, the mortality of all cases admitted with this anomaly (including nonoperative cases) is approximately 50%. The significant mortality in this condition is thus found in cases which are: (a) of the less common anatomical types, i.e., Types A, B, D, and E ("H") (Table 1); (b) premature, by weight; or (c) complicated by associated major anomalies. Unfortunately, these 3 groups constitute a majority (63% in the present series) of infants with this condition. Any major advance in the reduction of mortality must be directed specifically toward these
HAYS DM. An Analysis of the Mortality in Esophageal Atresia. Am J Dis Child. 1962;103(6):765–770. doi:10.1001/archpedi.1962.02080020782005
Customize your JAMA Network experience by selecting one or more topics from the list below.