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July 1962

Extracorporeal Hemodialysis in Children

Author Affiliations

Donough O'Brien, M.D., Pediatric Biochemistry Laboratory, University of Colorado Medical Center, Denver 20, Colo.; Departments of Pediatrics and Medicine, University of Colorado Medical Center.; Fellow of the National Foundation (Dr. Clapp); John and Mary Markle Foundation Scholar in Medical Sciences (Dr. O'Brien).

Am J Dis Child. 1962;104(1):45-52. doi:10.1001/archpedi.1962.02080030047007

The special role of extracorporeal hemodialysis in the treatment of renal failure has been extensively evaluated in adults,1-3 whereas only limited information is available on its use for children.4 A number of scattered reports indicate that hemodialysis can be used successfully in children for the treatment of a wide variety of renal and intoxication problems. Some of the clinical conditions in which dialysis has been used in children are: renal shutdown secondary to acute or chronic glomerulonephritis,5,6 transfusion reaction,6 bilateral cortical necrosis,5 meningococcal sepsis,6 sulfonamide toxicity,8 crush syndrome,8 anorexia nervosa8; to remove edema fluid7; for hyperkalemia,9 salicylate intoxication,10 or in other acute intoxications, and in uremia of unknown etiology.11

The object of this report is to present the results in 11 children, ages 3-15 years, subjected to dialysis during the past 3 years. These cases illustrate the

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