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July 1962


Author Affiliations

Director of Research Clinica Anglo Americana Lima, Peru

Am J Dis Child. 1962;104(1):97. doi:10.1001/archpedi.1962.02080030099015

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To the Editor: On Page 190 of your August, 1961, issue there appeared a very interesting article entitled "Plasma Volume as an Index of Total Fluid Loss" by Czaczkes and Abrahamov.

We could not help being surprised at the reported fluid losses in the moderately dehydrated and severely dehydrated groups. These have apparently been calculated from the difference between the admission weight and "normal" weight at the end of rehydration, 2 or 3 days after admission.

In our experience in the United States with well-nourished infants and here in Peru with severely malnourished infants, we have hardly ever encountered fluid deficits of such magnitude or such retentions of water in such a short period of time without gross edema. The only infants or children I have ever seen lose as much as 35% of their body weight have been grossly edematous patients with nephrosis or kwashiorkor who have diuresed fluid

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