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March 1963

Aseptic Meningitis Caused by ECHO 20

Author Affiliations

Henry G. Cramblett, M.D., Virology Laboratory, Wake Forest College, Bowman Gray School of Medicine, Winston-Salem, N.C.; From the Virology Laboratory, Departments of Pediatrics and Microbiology, Bowman Gray School of Medicine.

Am J Dis Child. 1963;105(3):295-296. doi:10.1001/archpedi.1963.02080040297013

The prototype strain (JV-1) of ECHO virus Type 20 was recovered during a study of respiratory illnesses among infants and children in an orphanage in 1956.1,2 In 1959, ECHO 20 was recovered from the feces of 4 patients with aseptic meningitis in Manitoba.3 The present report describes a child with aseptic meningitis, also studied in 1959, from whose cerebrospinal fluid ECHO 20 was recovered.

Report of a Case  A mentally retarded 8-year-old girl was admitted to the hospital for observation because she had fallen down a flight of stairs. On specific questioning, the mother stated that the child had had fever for 2 days prior to admission but had offered no complaints.On physical examination, the child appeared withdrawn, anxious, and was incapable of providing additional history. The temperature orally was 102.4 F with the remainder of the vital signs being normal. There was indication of meningeal irritation

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